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Sometimes I can open a JPG in Photoshop, work on it, and then save it. Other times when I try to save the file I get an "Could not complete your request because of a program error." If I then open another JPG or TIF or PS file and try to save it, I get the same error.

If I close and reopen Photoshop, I still get the same error.

If I restart the computer, then I can save my file, but sooner or later, I get the same error.

Usually, but not always, if I open the file using a different program and save the JPG file as a TIF, and then open Photoshop and try to save the file, I'm okay but after 10-15 minutes I'm back to the same error.  This problem has been going on for over a year or so.

I don't believe I have this problem on a different (Windows Vista) computer. What am I doing wrong?