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Dear forum members,

I am working with the first image shown below, which is a light micrograph of a mouse brain centered on the part of the brain called cerebellum (sponge-like structure occupying the central portion of the image). I would like to measure the surface area and the diameter of the cerebellum, and since I don't have any more specialized tools for this task, I am considering using Photoshop's built-in measurements tools for the job. To do the measurements, I need to select the entire cerebellum area (second image), but, as you can see, the biggest problem in creating the required selection are the brain furrows (folds). Since I'm a total noob at Photoshop, I need anywhere from 6 to 8 minutes to do this using the combination of quick selection (to select only the cerebellum part of the image), followed by manual deselection of furrows using brush tool in quick mask mode. Since I have ***a lot*** of these pictures to process, I was wondering whether any of the pros out here might suggest a faster way of making the desired selection.

Thanks everyone in advance!