So i think i got it
and it's probably crazy.
So algorimt would look like:
1. make new group with "background" image name ir "ground Zero" 
2. do all you can do without needed to flattern image (at some point it could happend)...all undestractive stuff...opacity/chanell mixer and so on.
3 . now you NEED image to be plain...merge all that group (just that group) in new layer, name it background2
4. make new group call it group2 put background2 in it.
5. do all you want and can do without flattering image or part of it.
Now you need plain it again for some reason (don't know what).
6. do what 1. said but call group3 and background3.
and so on and on until you finish
So what to do if you noticed that you need change let say something in ground Zero?
.....just do it! 
Now merge that ground Zero to new layer (just that group) name it background2 and replace background2 in group2
if you have group3 then do merge group2 (just group2) and name it background3 and replace it un group3....and so on on
hope you get a point.
the last merged group is result!
(group can be merged by holding ALT+ choosing Merge Group.
In that case you have all posible adjustments alive but most of all isn't "active" but with some action you "alive them".
I don't think that if there just a few adjustments that it's worth it but if you have hundreds then it could help.
You can make mask to some group but it will make it more dificcult to understand what a hell is going on.
Still think it's crazy but should work.
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